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THURSDAY, JUNE 12, 2025
Bharat's Covid-19 shot 50% effective at height of India infections - small study

Coronavirus chronicle

Reuters
24 November, 2021, 02:00 pm
Last modified: 24 November, 2021, 02:04 pm

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Bharat's Covid-19 shot 50% effective at height of India infections - small study

Covaxin, which Bharat Biotech co-developed with an Indian research body, received emergency-use authorisation in India in January even before the completion of the late-stage trial

Reuters
24 November, 2021, 02:00 pm
Last modified: 24 November, 2021, 02:04 pm
Nuns hold an elderly man as he receives a dose of COVAXIN coronavirus disease (Covid-19) vaccine manufactured by Bharat Biotech, at a home for elderly in Mumbai, India, August, 2, 2021. Photo :Reuters
Nuns hold an elderly man as he receives a dose of COVAXIN coronavirus disease (Covid-19) vaccine manufactured by Bharat Biotech, at a home for elderly in Mumbai, India, August, 2, 2021. Photo :Reuters

Bharat Biotech's vaccine was only 50% effective at preventing symptomatic Covid-19 in a high-risk population during a devastating second wave of infections in India this year, data gleaned from hospital workers showed.

The real world study for Covaxin, conducted April 15-May 15, compares with a 77.8% effectiveness rate in a late-stage trial of more than 25,000 participants that was conducted November 2020 to January 2021.

The new data analysed just over 1,000 Covid-19 cases with a test-negative control case group, matching by age and gender, according to the study which was published in the Lancet Infectious Diseases journal.

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The much lower effectiveness rate for the two-dose shot seen in the new study can possibly be attributed to the fact that the study was restricted to hospital employees who had a higher risk of being infected than the general population, that it was conducted during a surge in infections and also to the prevalence of the Delta variant at the time, the study concluded.

Covaxin, which Bharat Biotech co-developed with an Indian research body, received emergency-use authorisation in India in January even before the completion of the late-stage trial.

It is the only homegrown vaccine being used in India's vaccination programme, although it accounts for only about 11% of the 1.18 billion doses administered so far.

Covaxin has also been approved in countries such as Vietnam and Brazil. Bharat Biotech's US partner, Ocugen, has submitted a request to the US FDA for emergency use approval.

Top News / World+Biz

Bharat Biotech / Covid -19

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